Hepatic histology revealed liver parenchymal heterogeneity with fibrosing hepatopathy (AI F3/F4 METAVIR score), acute cholangiolitis, biliary duct dystrophy, ductular neogenesis without ductopenia, and intracytoplasmic AAT globules, without steatosis or significant inflammation (Fig. 1D). Here, SERPINA1 is linked to steatosis.