Notably, Angiogenic factor with G patch and FHA domains 1 (AGGF1) regulates liver fibrosis [35] and may contribute to Metabolic dysfunction-associated steatohepatitis (MASH) pathogenesis [37] just like Vanin-1 (VNN1) and Suv39h2, two histone methyltransferases [34]. The gene discussed is VNN1; the disease is metabolic dysfunction-associated steatohepatitis.