Consistent with the previous plotting comparing solid cancers versus MDS (Fig. 2), H2A/H2B dimer, H2B, macroH2A1.1/H2B, and macroH2A1.2/H2B dimers were detectable only in a few patients affected by the single solid cancer types (Fig. 3). This evidence concerns the gene H2BC21 and myelodysplastic syndrome.