MMP9 emerged to be the best performance indicator in differentiating between adenomyosis and endometriosis (AUC = 0.93; 95% confidence interval (CI) 0.86–1.00; p < 0.0001; Fig. 5B), followed by MMP11 (AUC = 0.82; 95% CI 0.70–0.94, p < 0.001). The gene discussed is MMP9; the disease is endometriosis.