The in vitro anticancer activity of 18 cephalosporin antibiotics (CAM, CUS, CAN, COS, CPH, CMS, LYT, CTD, CMH, CXS, CNS, CIS, CES, CAS, CASP, CZS, CTS and CDS) was evaluated on 6 human nasopharyngeal carcinoma cell lines with different histological characters (CNE1, CNE2, 5-8F, TW03, HONE1, and C666-1). This evidence concerns the gene TTR and nasopharyngeal carcinoma.