In the DIA dataset, several tyrosine-phosphorylated proteins were exclusively identified, including not only well-established regulators of the TLR4 signaling pathway (Tab2, Mapk3, and p38), but also RNA splicing factors (Ddx39b, Rbm17, Srsf1, Srsf6, Slu7, Tra2a, Tra2b, Ncbp2) and regulators of the ErbB signaling pathway (Crk, Grb2, Nck2, Pak4), which have been extensively studied in the context of cancer. Here, CRK is linked to cancer.