While much research effort has been dedicated to investigating Tau and αS LLPS22, aggregation kinetics43, fibril structure44, templated misfolding, and pathological toxicity in diseased models45, it is crucial to have a comprehensive understanding of the biochemical aspects of various proteins associated with LLPS and neurological disorders, particularly in the context of IDPs (intrinsically disordered proteins). Here, MAPT is linked to nervous system disorder.