ANXA5 and hepatocellular carcinoma: In research related to anti-NSCLC drugs, cucurbitacin B has been shown to be an effective anti-tumor agent in treating hepatocellular carcinoma and has been validated for its anti-NSCLC effects using the LLC-C57 Nude animal model and in vitro techniques such as MTT and Annexin V/7-AAD double staining [28].