At the time of preparing this manuscript, a recent RPGRIP1-LCA cohort study included one LCA patient who was also identified with this RPGRIP1: c.2108T>C p.(Ile703Thr) variant and classified as a VUS by the authors (Daich Varela et al., 2024). The gene discussed is RPGRIP1; the disease is Leber congenital amaurosis.