Pathogenic variants in over 20 genes are known to cause LCA, including retinitis pigmentosa GTPase regulator-interacting protein (RPGRIP1) (OMIM: 605446), which accounts for 5%–7% of cases (Beryozkin et al., 2021; Kumaran et al., 2017). This evidence concerns the gene RPGRIP1 and Leber congenital amaurosis.