Taken together, these results are suggestive of a potential route of Aβ-related atrophy independent of concurrent neurofibrillary tangles specifically in the fusiform gyrus, although other previous findings have found Aβ-related fusiform atrophy to be exacerbated by tau presence without being completely independent of it (Nosheny et al., 2019). This evidence concerns the gene MAPT and Atrophy.