ARMC5 and adrenal cortex adenoma: To identify differences in protein signaturesthat may reveal insights into disease-specific pathogenesis, we usedLC–MS/MS and bioinformatics to compare proteomic profiles ofnormal human adrenal (NHA) tissue, adrenocortical adenomas (ACA),adrenocortical carcinomas (ACC), and primary macronodular adrenocorticalhyperplasia (PMAH) tumors, with and without ARMC5 mutations.