Furthermore, biomarkers reported in the literature in ACC,such as Stathmin 1 (STMN1),, N-myc downregulated gene family 4 (NDRG4),, and phosphoglycerate dehydrogenase (PHGDH), validated in our proteomic analysis, were alsoassociated with aggressive behavior and poor patient outcomes in ACC(Figure S5). Here, PHGDH is linked to adrenal cortex carcinoma.