PTBP1 and Parkinson disease: Qian et al. employed delivery of AAV vectors encoding Ptbp1 shRNA as well as Ptbp1 antisense oligonucleotides (ASO) into the substantia nigra of 6-hydroxydopamine-treated (6-OHDA) mice modeling Parkinson’s disease (PD) and reported generation of new neurons and reversal of PD phenotypes (Qian et al., 2020).