SOX4 and non-small cell lung carcinoma: For example, in endometrial cancer cells, propofol inhibits proliferation, migration and invasion, and promotes apoptosis by downregulating SOX4 expression, which is associated with inactivation of the Wnt/β-catenin signaling pathway, indicating that the Wnt/β-catenin-SOX4 axis may be involve in the apoptosis of NSCLC cells (74).