For example, in endometrial cancer cells, propofol inhibits proliferation, migration and invasion, and promotes apoptosis by downregulating SOX4 expression, which is associated with inactivation of the Wnt/β-catenin signaling pathway, indicating that the Wnt/β-catenin-SOX4 axis may be involve in the apoptosis of NSCLC cells (74). This evidence concerns the gene SOX4 and endometrial cancer.