To establish the relation of MKI67 with our target genes ccorrelation analyses were performed using ENCORI database which revealed consistent co-expression patterns between MKI67 and ESPL1 (R = 0.827), E2F8 (R = 0.816), hsa-let-7b-5p (R = −0.153), and TMPO-AS1 (R = 0.540) in breast cancer and the same correlations were corroborated (Supplementary Figures S4A–G). Here, E2F8 is linked to breast carcinoma.