The study performed the data mining of The Cancer Genome Atlas (TCGA) using various web-based computational tools, including TIMER 2.0, UALCAN, FIREHOSE, TISIDB, GEPIA2, OncoDB, TCGA Portal, TCGAnalyzeR v1.0, bc-GenExMiner v5.0, TNMplot, and DriverDBv4 to compare ESPL1 expression in tumor vs. normal tissues across pan-cancer and BC subtypes. Here, ESPL1 is linked to breast cancer.