NEAT1 and Tangier disease: We found that PBMC NEAT1 and plasma iron levels were significantly and positively correlated with the Gensini scores of CHD patients (NEAT1: r = 0.4537, p < 0.0001; iron: r = 0.4264, p < 0.0001; Figure 1A,B), suggesting that NEAT1 upregulation and iron overload are associated with AS.