We used FIMO to predict CTCF binding sites on the GRCh38 reference genome, and used the FIMO scores with four other different features (CTCF binding motif, DNA accessibility, h3k4me3, h3k27me3, and h3k27ac) to train a Random Forest predictor for CTCF binding on three different control AD patients, using CTCF ChIP-seq information as gold standard; 52 435 CTCF binding sites were predicted by FIMO. Here, CTCF is linked to Alzheimer disease.