Interestingly, unlike in ZSD patients (Takashima et al., 2017), the brains of pex1–/– zebrafish showed significantly lower levels of saturated C22 and C24 (Supplementary Figure 2B), and overall saturated FA levels were consistently decreased in pex1–/– brain and liver samples, in stark contrast to the increased PUFA levels (Supplementary Figures 2B–D, 3). The gene discussed is PEX1; the disease is peroxisome biogenesis disorder.