FLI1 and Ewing sarcoma: For instance, one study identified 9 AS variants of EWS-FLI1 (Ewing sarcoma friend leukemia integration 1) and one AS variant of EWS-ERG (Ewing sarcoma erythroblast transformation-specific gene) fusion genes in 23 EwS tissue samples, involving EWSR1 (Ewing sarcoma RNA binding protein 1) exon 8 and multiple exons of FLI1, such as exons 5 and 8 [189].