In contrast, the molecular biomarkers discussed in this article—such as Intestinal Fatty Acid-Binding Protein (I-FABP) and Serum Amyloid A (SAA)—are released into the blood or urine at the very early stage of intestinal mucosal injury, providing a critical “time window” for the early identification of NEC. The gene discussed is FABP2; the disease is necrotizing enterocolitis.