CXCL8 and necrotizing enterocolitis: Additionally, a study evaluating 92 inflammation-related proteins using a high-throughput OLINK proteomic platform found that 11 biomarkers (with upregulated expression, including IL-8, IL-24, CCL20, OPG, TSLP, TRAIL, MMP-10, CXCL1, MCP-4, TNFSF14, and LIF) hold high value in identifying NEC and determining its severity (133).