FABP2 and necrotizing enterocolitis: Additionally, a study by Saran et al. (79) pointed out that the urinary I-FABP/creatinine ratio (urinary I-FABP/Cr) further optimizes diagnostic efficacy—when this ratio is 3.6 pg/mmol, the sensitivity and specificity for diagnosing NEC stage II/III reach 96% and 99.5%, respectively—providing a more reliable quantitative indicator for the early accurate diagnosis of NEC.