NOS2 and Pseudomonas infection: Macrophage iNOS/NO acts as an inter-cellular anti-ferroptotic mechanism: macrophage-derived NO prevents phospholipid peroxidation (notably 15-HpETE-PE) in adjacent epithelial cells and protects cells from ferroptosis (e.g., during Pseudomonas infection). This is a clear anti-ferroptotic mechanism.