PGR and invasive breast carcinoma: Core needle biopsy was taken from the lump in the nine o'clock position, which showed invasive breast carcinoma of no special type, grade I, estrogen receptor (ER) 2+ positivity in 60% of tumor cells (Allred score = 6/8), progesterone receptor (PR) negative, HER2/neu negative, with Ki-67 of 5%.