Among the transcriptional regulators, SNAI1 (Snail) acts as a master repressor of epithelial markers—particularly CDH1 [15] thus orchestrating the EMT program essential for metastasis, while SNAI2 (Slug) similarly represses epithelial genes and governs cellular plasticity during EMT [16], contributing to cancer progression and therapeutic resistance. This evidence concerns the gene SNAI1 and cancer.