GO and KEGG enrichment analyses identified multiple immune-associated pathways such as antigen binding, immunoglobulin complex, immunoglobulin production, production of molecular mediators of the immune response and immunoglobulin receptor, reinforcing the hypothesis that STX16 may modulate the tumor immune microenvironment (TIME) by modulating the expression and activity of key immune-related genes and proteins. This evidence concerns the gene MPIG6B and neoplasm.