We further conducted a ChIP-seq experiment targeting FOXA1, a primary cognate TF of the eSNPs, in two prostate cancer cell lines (LNCaP19, derived from a donor of European ancestry and MDA PCa 2B20, derived from a donor of African ancestry) to assess the functional impact of eSNPs on TF binding disruption. The gene discussed is FOXA1; the disease is Familial prostate cancer.