In particular, the polymorphism named ApaI (rs7975232) and TaqI (rs731236) of the VDR gene have been extensively studied and shown a positive association with obesity in Saudi, Iranian, Korean, Greek, and Chinese populations [16,21–26] whereas negative associations have also been reported [16,23,27–29]. The gene discussed is VDR; the disease is obesity due to melanocortin 4 receptor deficiency.