However, the number of cases analysed to date is relatively small.<h4>Methods and results</h4>Twenty testicular AGCTs were analysed de novo using two different next-generation sequencing (NGS) panels that cover sex cord-stromal tumour (SCST)-relevant genes, including FOXL2, CTNNB1, FH and DICER1. Here, CTNNB1 is linked to neoplasm.