ABCB1 and atrial fibrillation: In this ENVISAGE-TAVI AF on-treatment analysis, patients received edoxaban 60 mg once daily—adjusted to 30 mg if they met ≥1 eDAC (creatinine clearance 15 to ≤50 mL/min, body weight ≤60 kg, or concomitant use of potent P-glycoprotein inhibitors)—or VKA.