Using a qRT-PCR assay, high expression levels of pro-inflammatory cytokine genes, including IL6, IL15, IFNγ, TNFα, CXCL15, IL18, and IL1β, were confirmed in ZIKV-infected placentas, suggesting that ZIKV infection may trigger placental inflammation (Fig. 1H). The gene discussed is IL1B; the disease is Zika virus infectious disease.