FOXP3 plays a vital role in immune stability and autoimmunity prevention.[37] Prior studies have debated the impact of FOXP3 polymorphisms on cancer susceptibility.[41] FOXP3 is an immune‐related gene essential for Treg function.[22, 70] Our findings reveal a significant association between the FOXP3 rs3761549 “T” allele and cervical cancer, suggesting its role as a potential biomarker for disease development and prognosis. This evidence concerns the gene FOXP3 and Autoimmunity.