On postoperative day 2, the barbed suture group had significantly lower WBC levels (P = 0.039), higher Hb levels (P = 0.029), higher PLT levels (P = 0.041), lower CRP levels (P = 0.027), lower VAS pain scores (P < 0.001), higher SF-36 scores (P < 0.001), lower HADS-Anxiety scores (P = 0.012), and lower HADS-Depression scores (P = 0.015) (Table 4). Here, GSTM1 is linked to major depressive disorder.