Genes with reported anti-tumor functions, including SCGB1D2 (Secretoglobin Family 1D Member 2, lipophilin B), FKBP5, CD52, DLK1, GALNT9, GNG2, GDNF, and TMEM35A, were significantly upregulated after CUDC-907 + MPA treatment and validated by RT-PCR. The gene discussed is TMEM35A; the disease is neoplasm.