M: Male patient; F: Female patient; MODY: Maturity onset diabetes of the young; GLP-1: Glucagon-like peptide-1; GIP: Glucose-dependent insulinotropic polypeptide; KT: Kidney transplant; PDR: Proliferative Diabetic Retinopathy; MI: Myocardial infarction; PVD: Peripheral vascular disease; Dapa: Dapagliflozin; VUS: Variant of uncertain significance; ↓: reduction; het: heterozygous; homo: homozygous. The gene discussed is GCG; the disease is peripheral vascular disease.