('diabetic ketoacidosis'/exp OR 'DKA' OR 'diabetic ketoacidosis') AND ('hypoglycemia'/exp OR 'hypoglycemia' OR 'low blood glucose') AND ('insulin therapy'/exp OR 'insulin infusion' OR 'insulin regimen') AND ('fluid therapy'/exp OR 'intravenous fluids' OR 'rehydration') AND ([randomized controlled trial]/lim OR [cohort]/lim OR [clinical study]/lim). This evidence concerns the gene INS and Hypoglycemia.