The Spearman’s correlation analysis showed that plasma HMOX1 levels were positively correlated with 2-h Glu, WC, fasting Ins, HOMA-IR, TG/HDL-C ratio, BMI, 2-h Ins, TC, fasting Glu, FAI, T-AOC, apoB, and WHR in patients with PCOS (r = 0.138, 0.132, 0.132, 0.129, 0.127, 0.118, 0.105, 0.093, 0.092, 0.087, 0.085, 0.080, and 0.079, respectively; P < 0.05). The gene discussed is APOB; the disease is polycystic ovary syndrome.