TTF1 and adenocarcinoma: The liver biopsy results on May 16, 2024 indicated the presence of adenocarcinoma infiltration or metastasis, with immunohistochemical findings consistent with pulmonary adenocarcinoma (Fig. 1), demonstrating positive staining for NapsinA, CK7, CK19, and TTF-1, focal positivity for P16, moderately positive P53 expression, and a Ki67 proliferation index of approximately 10%, while being negative for CK20, ER, and partial response.