Albumin and globulin are major serum proteins that represent systemic inflammation.[31] GGT is a marker of hepatic injury, and its elevation is associated with an increased risk of chronic diseases.[32] Although mostly used as an acute-phase inflammatory marker, a moderate increase in CRP levels has been observed in chronic inflammatory states, including malignancy.[33] CA 19-9 is the most valid serum tumor marker for PC diagnosis and monitoring of pancreatic cancer. The gene discussed is CRP; the disease is familial pancreatic carcinoma.