The additional AGP-1 protein in septic shock sera is predictably from hepatic origins, however, since neutrophils are also known to produce, store and upon activation release AGP-1 displaying glycosylation features that are different to those carried by liver-derived AGP-1 (77), future efforts are required to determine if septic shock survivors and nonsurvivors carry AGP-1 from different tissue origins as this may explain the different glycosylation patterns observed across the two patient groups. This evidence concerns the gene ORM1 and Shock.