Brain tissues from six individuals with different types of tauopathy (AD, CTE, Pick’s disease [PiD], progressive supranuclear palsy [PSP], corticobasal degeneration [CBD], and frontotemporal dementia and Parkinsonism linked to chromosome 17 with a P301L mutation in MAPT) were used for the extraction of sarkosyl-insoluble tau seeds of known structure. Here, MAPT is linked to Pick disease.