BCR and type 1 diabetes mellitus: ,31 An unbiased immune repertoire study of immunoglobulin H (IgH) sequences identified in pancreatic islets, pancreatic and “irrelevant” lymph nodes, spleen, and peripheral blood from individuals with established T1D reported overabundance of some VH gene segments, but did not allow for BCR antigen specificity to be determined, as light chains were not sequenced.32