Continuing with the studies, it was evidenced that the high consumption of a high-calorie diet, high in fat, can aggravate the manifestations of hepatic steatosis caused by the induction of periodontitis due to ligatures, with markedly increasing levels of MDA, GSH, steatosis, HDL, total weight, cholesterol, uric acid, and ALT.16 This evidence concerns the gene GPT and fatty liver disease.