Additionally, severe dengue cases showed elevated tetracycline resistance genes (tet(A), tet(C)) along with aminoglycoside (ANT(3’‘)-IIa) and MDR ARGs (amrA, TEM-171, TEM-230, TEM-98, MexJ, OprM, SHV-7), as well as a single peptide resistance gene (cprR). Here, OPRM1 is linked to dengue disease.