We identified a change in proteins involved in melanoma progression by their growth and proteins like proliferation inducing properties (peptidyl‐prolyl cis/trans isomerase (Pin1), the malignant T‐cell amplified sequence 1 (MTCS1)), by redox control (epididymis secretory sperm binding protein), and by the property to suppress apoptosis (ubiquinone oxidoreductase), among others in CREB overexpressing cells (Figure 5A,B). Here, PIN1 is linked to melanoma.