This placental vulnerability was mirrored in male fetal brains, demonstrating the downregulation of primary neurodevelopmental genes, such as Mef2c, Neurod2, Neurod6, and Zeb2. Mef2c is thought to be associated with cognitive deficits and increased schizophrenia risk in patients [33]. The gene discussed is NEUROD2; the disease is schizophrenia.