Additionally, male-specific downregulation of aconitate decarboxylase 1 (Acod1) and Ccl2/Ccr2, genes associated with impaired anti-infection protection [31] and placental leukopenia following maternal stress [32], respectively, was observed, indicating immune dysregulation and compromised anti-infection capacity. The gene discussed is CCL2; the disease is Decreased total leukocyte count.