A second interesting downregulated protein is serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (protein 2ABD, gene PPP2R2D), which is the regulatory subunit of widely expressed phosphatase that plays a key in the control of mitosis entry and exit, is involved in regulation of cellular division and signal transcription and also acts as a tumour suppressor32. The gene discussed is PPP2R2D; the disease is neoplasm.