AKT1 and cancer: Furthermore, KEGG pathway analysis identified significant enrichment in 105 pathways, including Pathways in cancer, PI3K-Akt signaling pathway, Human papillomavirus infection, MAPK signaling pathway, Endocytosis, Neuroactive ligand-receptor interaction, Ras signaling pathway, HTLV-I infection, Regulation of actin cytoskeleton, and Focal adhesion (Fig. 3B).