Furthermore, the protein expression of interferon gamma (IFNγ) was also increased in tumor‐infiltrated CD8+ T cells isolated from LLC1‐bearing mice co‐administered with anti‐PD‐L1 antibodies at ZT16 and AMD3100 at ZT16, but not AMD3100 at ZT4 (Figure 6D,E). This evidence concerns the gene CD274 and neoplasm.