Conclusion: Dyslipidemia in dyspeptic patients without H. pylori infection was associated with higher TyG indices; coexisting dyslipidemia and H. pylori infection were associated with increased BMI and WC. No significant differences were observed for HbA1c or fasting glucose between the groups, although the TyG index varied markedly, reflecting discrete changes in insulin sensitivity. Here, INS is linked to metabolic syndrome.