Compared to the MDD group, the SCZ group exhibited higher counts of leukocytes, lymphocytes, and monocytes, as well as elevated levels of ALT, AST, LDL-C, UA, albumin, UHR, UAR, UCR, NHR, LHR, MHR, and PHR; conversely, the neutrophil count and HDL-C level were lower (p <0.05). The gene discussed is ALB; the disease is major depressive disorder.