In the exploration of prognostic factors for DFS, we found that CEA, CA125, CA199, AFR, GGT, PLR, TNM staging (8th), tumor number, tumor size, tumor differentiation, satellite lesion, MCI, MVI, perineural invasion and lymph node metastasis were significantly associated with DFS (all P < 0.05). The gene discussed is CEACAM5; the disease is neoplasm.