Univariate analysis identified prognostic factors associated with OS, including CEA, CA125, CA199, AFR, AST, GGT, TBIL, NLR, PLR, Child-Pugh, tumor number, tumor size, tumor differentiation, satellite lesion, MCI, perineural invasion and lymph node metastasis (all P < 0.05). This evidence concerns the gene CEACAM5 and neoplasm.