OA‐rich EN significantly activated PPARγ, inhibited STAT‐1 phosphorylation, promoted STAT‐6 phosphorylation, reduced iNOS expression, and up‐regulated the expression of Arg‐1, Fizz 1, and Ym 1, and these effects were greater than those in the IBD + EN group (Figure 2). The gene discussed is STAT6; the disease is inflammatory bowel disease.