CD274 and lung carcinoma: This is the case of specific intermolecular interactions between T cells and lung cancer cells expressing programmed death ligand 1 (PDL1).[260] The PDL1 biomarker appears in early stage resected lung cancer cells.[261] The presence of nivolumab in the media increased the adhesion force of this biological system of tens to hundreds of pN, as evaluated at different timescales.